There are several medical studies — such as two conducted by the Department of Radiation Oncology at the Holden Comprehensive Cancer Center for the University of Iowa, and the National Institutes of Health’s National Institute of Neurological Disorders and Stroke, for example — that show the ketogenic diet is an effective treatment for cancer and other serious health problems. (12)

The end result is staying fueled off of circulating high ketones (which are also sometimes called ketone bodies) — which is what’s responsible for altering your metabolism in a way that some people like to say turns you into a “fat-burning machine.” Both in terms of how it feels physically and mentally, along with the impact it has on the body, being in ketosis is a very different than a “glycolytic state,” where blood glucose (sugar) serves as the body’s energy source.
After the initial transition period (often referred to as the fat-adaptation or keto-adaptation period), most people find they gain a ton of mental and physical energy.  They don’t have energy crashes in the afternoons and they often sleep a bit less but wake up feeling refreshed.  They also tend to eat less because they don’t feel hungry or have cravings.
Researchers believe that the ketogenic diet can also help patients with schizophrenia to normalize the pathophysiological processes that are causing symptoms like delusions, hallucinations, lack of restraint and unpredictable behavior. One study found that the ketogenic diet lead to elevated concentrations of kynurenic acid (KYNA) in the hippocampus and striatum, which promotes neuroactive activity. Some studies even point to the elimination of gluten under the ketogenic diet as a possible reason for improved symptoms, as researchers observed that patients with schizophrenia tended to eat more carbohydrates immediately before a psychotic episode. (15)
Some dairy products can be used in moderation, such as heavy whipping cream and most cheeses. This would depend on your individual sensitivity to dairy (some people digest it better than others) and on the particular type of food. Milk contains a relatively high amount of carbs (4 to 5 g per 100 ml) and should be limited or avoided, as well as store-bought yogurt. You can, however, have unsweetened almond milk or heavy cream. Make sure to check the labels carefully when buying dairy products, as some of them contain a rather high amount of carbs. Some people also find that eliminating dairy helps them to lose weight faster, which might be something you want to consider in case you stall.
It feels like everyone is talking about the keto diet — the high-fat, low-carb eating plan that promises to turn your body into a fat-burning machine. For that reason, keto has surged in popularity over the past year as a lose-weight-fast strategy. Thank Hollywood A-listers and professional athletes like Halle Berry, Adriana Lima, and Tim Tebow who’ve publicly touted the diet’s benefits, from shedding weight to slowing down aging. Here’s everything you need to know about going keto — and how to do it the Bulletproof way.

The biggest draw for me is how many of those who’ve tried it say they don’t get hungry. The possibility of that blows my mind, as someone who’s used to any sort of calorie restriction meaning hours of feeling hungry every day. It’s tantalizing enough that I at least want to try. And what have I got to lose, right? I’m already morbidly obese; it’s hard to imagine screwing this up so bad it makes that worse.


For any individual with diabetes, discussing dietary changes — especially those as dramatic as the ones the ketogenic diet requires — with your healthcare team is essential. Because carbohydrates are broken down into glucose in the blood, cutting carbohydrates from your diet could cause levels to crash rapidly depending on your current medication regimen. Such a change may require significant adjustments to medication and insulin to prevent dangerous side effects such as low blood sugar, called hypoglycemia. (8)

Lots of apps and website offer keto diet challenges—basically, a blueprint for the keto diet with a fixed starting and ending point (they typically last for a week to a month, though some may be longer). Speaking of apps, plenty of keto-centric ones are right at your fingertips (a.k.a., your smartphone), like the KetoDiet app, which can help you calculate your macros and track your keto diet effectively.
Although a standard ketogenic diet is even more restrictive in terms of carb intake, a “moderate keto diet” (just as some folks have followed a modified Atkins diet) is another option that will very likely still be able to provide substantial weight loss results and other improvements in symptoms. Including slightly more carbs can be very useful for maintenance, allow for more flexibility, provide a higher fiber intake, and overall may feel more sustainable long term socially and psychologically.

Hi Sia, welcome to the wonderful world of keto! I would start simple – eat whole foods like avocado, protein, and dark veggies. Download MyFitnessPal or CarbCounter apps to track your macros for you. What works best for me is planning out my meals ahead of time. Ill meal prep my food then log it into MyFitnessPal app so I know I am on target then the next day, eat only what I’ve logged. Its the perfect way to make sure you have enough food that already prepared and the best way to stick to macros. Hope that helps!


Quick update – been doing a keto-type diet for a couple of months now. My BP is down to the lowest it’s been in something like 10 years, though still on 1/2 dose for my meds. I’ve lost about 30 pounds in the last 4 months (give or take a bit as I’m not sure exactly where I started). I’ll admit I still use Truvia and will have a Coke Zero every now and then, but eliminating the wheat and corn breads and sugars to reduce my carb intake to < 50g/day on average has made a huge difference. (I'm sure some still sneaks in with some of the food I eat out, but for the most part it's pretty good.)

Oh man, this is a great read. Entertaining and full or resources and digestible content even though it is a long article. But I appreciate the research you went through it. I remember 5 years ago researching about Keto diet took forever because of how spread out the sources were. This is great work as a guide. Thanks for the article. Before reading this article I thought the requirements were too strict, but now that I read it, I am already doing a third of that list. I am trying IF right now, but I think this will help me with my satiety problem with meals, plus help me with weight loss. Thanks for the motivation and information Steve. I am starting my plan of attack and try a Keto diet.

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