• Multiple Sclerosis: In a small 2016 study, patients with multiple sclerosis (MS) were put on a ketogenic diet. After six months, they reported improved quality of life, as well as physical and mental health improvements. Before doctors or researchers can make a connection between keto and MS, they need bigger sample sizes and more thorough research. Still, the preliminary findings are exciting.
KetoVale‘s Tip:  Exogenous ketones are NOT a magic pill or a carb blocker. You should be making better choices about your diet meal plan first and then ask yourself if you want to or how you can supplement afterward to help out. Remember it’s a supplement and not supposed to be used as an eraser to erase eating choices (by definition, supplement is a thing added to something else in order to complete or enhance it). It’s like building muscles, you can take supplements, but if you don’t workout and eat right, the muscles won’t show up. The supplements aren’t going to lift those heavy weights for you. There’s no magic bullet.
After about two to seven days of following this eating routine, you go into something called ketosis, or the state your body enters when it doesn't have enough carbs for your cells to use for energy. Then it starts making ketones, or organic compounds that your bod then uses in place of those missing carbs—and oh, it also burns fat for more energy, says Beth Warren, R.D., founder of Beth Warren Nutrition and author of Living A Real Life With Real Food.
To prevent side effects such as the keto flu, begin transitioning your meal plan gradually. Start by understanding how many carbohydrates you take in most days. Then begin slowly reducing your carbohydrate intake over a period of a few weeks while gradually increasing your intake of dietary fat to keep your calories the same. You should also make sure to seek guidance from a professional to make sure this plan works best for you and your health goals. “See a dietitian and adapt the diet to fit your long-term needs,” Spano recommends.
Use our keto calculator to calculate the exact macros you should be eating. Remember, substituting more fat for carbs or protein is almost always ok. In fact, if you’re worried about losing muscle mass because of decreased protein consumption, you may not need to worry. There has been evidence that while in a state of ketosis your body actually maintains protein better than in a standard diet.

To be confident about being in ketosis, especially at the beginning when you're not quite sure how you should feel, it’s best to measure your ketone levels.  By monitoring your ketone levels, you can assure that you’re doing the diet correctly and make dietary adjustments based on what you measure. People also respond to diet and exercise differently, so the best way to cater the keto diet to your own biology is to measure.
The second tip is to “carb-up”, meaning to eat high fat, low carb all day, and at night basically eat all carbs, no fat. Carbs like sweet potatoes, plantains, and grains, are some of the prefered foods when practicing “carb-up”. The reason why the “carb-up” practice can be helpful is because, once you are fat-adapted, your body burns carbohydrates first, and then goes into the fat-burning mode but, once you increase the amount of carbs eaten, your body’s ability to better burn fat is increased. To sum up “carb-up”: helps you go from fat-adapted back to the fat-burning mode.
Although studies have shown that the keto diet can reduce seizures for children with epilepsy, there is no evidence indicating that keto helps with other brain disorders or improves mental cognition, according to Harvard Health Publishing. Some studies show that keto may lower blood sugar for people with type 2 diabetes, but there is not enough long-term research to determine whether it’s safe and effective for diabetics.
Bonnie J. Brehm, Randy J. Seeley, Stephen R. Daniels, and David A. D’Alessio, “A Randomized Trial Comparing a Very Low Carbohydrate Diet and a Calorie-Restricted Low Fat Diet on Body Weight and Cardiovascular Risk Factors in Healthy Women,” The Journal of Clinical Endocrinology & Metabolism: Vol 88, No 4; January 14, 2009. http://press.endocrine.org/doi/full/10.1210/jc.2002-021480.
The keto diet works for such a high percentage of people because it targets several key, underlying causes of weight gain — including hormonal imbalances, especially insulin resistance coupled with high blood sugar levels, and the cycle of restricting and “binging” on empty calories due to hunger that so many dieters struggle with. Yet that’s not a problem with what’s on the keto diet food list.

Con: Results can vary depending on how much fluid you drink. By drinking more water, you dilute the concentration of ketones in the urine and thus a lower level of ketones will be detected on the strips. The strips don’t show a precise ketone level. Finally, and most importantly, as you become increasingly keto-adapted and your body reabsorbs ketones from the urine, urine strips may become unreliable, even if you’re in ketosis.


The removal of many grains and fruits with such a large emphasis on fats can bring about its own set of side effects. “If not done properly — with most of your carbohydrates coming from fiber-rich vegetables — you may not be getting enough fiber, which can lead to constipation,” says Chris Mohr, PhD, RD, a sports dietitian based in Louisville, Kentucky, and co-owner of MohrResults.com. (5)
One of the secrets of getting into ketosis faster is by fasting, since this helps burn off stored glycogen, so trying intermittent fasting can help you on your way. While it isn’t necessary to be on a ketogenic diet, doing IF while on a ketogenic diet can be very helpful. Most people who do IF don’t even think about food until late in the morning because it becomes natural to wait until later to eat.
Beverages: It’s common to become dehydrated on the keto diet. Your insulin levels drop when you restrict carbs, and low insulin makes it harder for your body to retain sodium and water.[9] Drink plenty of plain water, and sip on bone broth to replenish electrolytes, especially during the first couple of weeks when your body is adjusting to the new diet.
The ketogenic, or "keto," diet — which first became popular in the 1920s as a treatment for epilepsy and diabetes— limits carbohydrates to no more than 50 grams a day, which is the rough equivalent of a plain bagel or a cup of white rice. By comparison, dietary guidelines from the US Department of Agriculture recommend from 225 to 325 grams of carbs a day.
Other forms of ketogenic diets include cyclic ketogenic diets, also known as carb cycling, and targeted ketogenic diets, which allow for adjustments to carbohydrate intake around exercise. These modifications are typically implemented by athletes looking to use the ketogenic diet to enhance performance and endurance and not by individuals specifically focused on weight loss.

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If you talk to keto aficionados, you’ll find many save leftovers from dinner for the next day’s lunch. Cook once, eat twice—your keto diet menu for lunch is solved. If you don’t like leftovers or if you’re craving something different for lunch, the mid-day meal can be as simple as a scoop of chicken salad. Or, hit the salad bar at a local grocery store and top a bowl of greens with some good-fat goodies. You can also try one of these simple keto lunches:
[i] Hussein M Dashti, MD PhD FICS FACS, Thazhumpal C Mathew, MSc PhD FRCPath, Talib Hussein, MB ChB, Sami K Asfar, MB ChB MD FRCSEd FACS, Abdulla Behbahani, MB ChB FRCS FACSI PhD FICS FACS, Mousa A Khoursheed, MB ChB FRCS FICS, Hilal M Al-Sayer, MD PhD FICS FACS, Yousef Y Bo-Abbas, MD FRCPC, and Naji S Al-Zaid, BSc PhD. "Long-term effects of a ketogenic diet in obese patients"
There are reasons a strange diet like this has stuck around since the 1920's.  A diet like keto that is low in sugar lowers blood glucose and insulin levels has several positive effects on the body, especially in overweight or obese people. The ketogenic diet gives your body the chance to re-adjust its glucose and insulin levels.  In addition, there are health benefits that will enhance daily life, as well as help treat disease.  Check out these benefits of the ketogenic diet:
It comes down to simple mathematics. In order to stay in ketosis, you need to eat a very very low number of carbs. And if you eat too much protein, this can actually knock you out of ketosis as well. Therefore, if you’re eating almost no carbs, and you are eating moderate amounts of protein, the ONLY remaining macronutrient you can consume to fill you up each day would be fat. Add in that consuming fat allows you to stay in ketosis, and you are consuming a high fat, medium protein, low carb diet.
I’ve always heard that the brain functions well on ketones. Gluconeogenisis typically reduces ketosis, though as well? This is the first time I’ve heard anyone say the brain can’t use anything but glucose. I know there’s *preferred* sources of fuel over others, but I was also fairly certain other sources were fine.. or humans might be in a bit of trouble.

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