Unfortunately, there's no long-term data on ketogenic diets versus other diets. In a 2015 Italian study, those on a ketosis diet lost 26 pounds in three months. About half of the participants stayed on the diet for a year but lost little additional weight in the next nine months. People in a 2014 Spanish study who followed a very-low-calorie ketogenic diet lost an average of 44 pounds in a year”but a third of them dropped out, possibly because it was too hard to maintain.
Other experts say the long-term accumulation of ketones could be harmful. œThose ketones are emergency fuel sources, and we're not meant to run on them long-term, says Kristen Kizer, a registered dietitian at Houston Methodist Hospital. œKetones are negatively-charged molecules, which means they're acidic. When you build up ketone bodies in your system, you're building up acid. One of the ways your body buffers acid is by pulling calcium from your bones. Kizer also notes that the diet isn't very balanced and involves a very high intake of animal products, which generally do not protect against cancer, diabetes, or other diseases.
If you talk to keto aficionados, you'll find many save leftovers from dinner for the next day's lunch. Cook once, eat twice”your keto diet menu for lunch is solved. If you don't like leftovers or if you're craving something different for lunch, the mid-day meal can be as simple as a scoop of chicken salad. Or, hit the salad bar at a local grocery store and top a bowl of greens with some good-fat goodies. You can also try one of these simple keto lunches:

There are variations of the ketogenic diet that are implemented for a variety of reasons. One of the top reasons these variations are used are for athletes who are not getting the necessary energy required for their intense workouts. There are also those who enjoy the benefits of ketosis, but they just do not feel the same without a carb refeed day every now and then.
So people saying that “ despite the lack of scientific support “ likely have a financial reason to say it. Some of these products are sold under something like a multi-level marketing arrangement, so sales people are entirely paid based on commission. For example, the company Prüvit sells drinkable ketones, called KETO//OS with a multi-level marketing structure.
In a standard American diet, the diet is composed of a lot of carbohydrates - enough to keep the body using glucose as its main energy source. This is fine, but requires frequent eating (every few hours) to keep energy levels up and during this time your body stores extra glucose as fat.[1] This state prevents the body from burning its fat stores as energy because it is constantly using glucose.
I've always heard that the brain functions well on ketones. Gluconeogenisis typically reduces ketosis, though as well? This is the first time I've heard anyone say the brain can't use anything but glucose. I know there's *preferred* sources of fuel over others, but I was also fairly certain other sources were fine.. or humans might be in a bit of trouble.

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