In addition to helping with weight loss, the Keto Diet has been used to treat epilepsy[9], help with Type II diabetes[10], polycystic ovary syndrome [11], acne [12], potential improvement in neurological diseases (Parkinson’s[13] and multiple sclerosis[14]), certain types of cancer[15], and reduces the risk factors in both respiratory and cardiovascular diseases[16]. Emerging studies are digging into its effects on Alzheimer’s [17]and other conditions as well.
• Standard ketogenic diet (SKD) — SKD is the type I typically recommend for most people, because it is very effective. It focuses on high consumption of healthy fats: As I explain in my book, "Fat for Fuel," you should aim for having 70 to 85 percent of your total daily calories to come from healthy fats. For your protein intake, the general rule of thumb is to follow the formula of 1 gram of protein for every kilogram of your lean body mass.
From the early understanding of the keto research and literature, it looks like we're just scratching the surface understanding some of the potential therapeutic roles of the keto diet. While it's unclear if it's any better or worse than any other diet for weight loss, the reality is that there is no one-size-fits-all model for diets. This doesn't even consider that weight-loss diets, in general, don't really work. While researchers can't agree on a specific statistic, it's commonly accepted that the vast majority of dieters will regain the weight lost (and often pack on extra pounds, as well). The long-term outcome of the keto diet is likely to be no different, especially given how challenging and restrictive it is to maintain.
Basically, the role of exogenous ketones is to boost the amount of ketones in your body. These products do work wonders if, after a long time on a keto diet, you don’t feel energized or generally don’t feel like you are at your best. Ultimately deciding to take exogenous ketones or not comes down to how you feel on your keto diet and trying to find a product with the highest possible quality.
Most alcoholic beverages don’t list the ingredients or nutritional information on the label, so be prepared and check your favorite drinks online so you know your limits beforehand. Most apps and trackers list many types of alcohol in their database, and this is the easiest way to be sure of what you’re drinking. Be warned, when you’re in ketosis your alcohol tolerance will go down, so you might not want to drink as much as you might be used to.
Aside from carb flu, be warned that staying in long-term, continuous ketosis may have drawbacks that may actually undermine your health and longevity. To stay on the safe side, I recommend undergoing a cyclic ketogenic diet. The "metabolic magic" that ketosis brings to the mitochondria actually occurs during the refeeding phase, not during the starvation phase.
This process of burning fat provides more benefits than simply helping us to shed extra weight — it also helps control the release of hormones like insulin, which plays a role in development of diabetes and other health problems. When we eat carbohydrates, insulin is released as a reaction to elevated blood glucose (an increase in sugar circulating in our blood) and insulin levels rise. Insulin is a “storage hormone” that signals cells to store as much available energy as possible, initially as glycogen (aka stored carbohydrates in our muscles) and then as body fat.
“A lot of folks find that batch cooking once or twice a week saves a tremendous amount of time and keeps you from spending every evening in the kitchen,” Weaver says. “When keto meal planning, you want to follow general good meal planning practices, like shopping for the week’s food all at once, which helps to save money, and prepping your vegetables when you get home. These 10 keto recipes are so good you’ll forget you’re on a diet.
Beverages: It’s common to become dehydrated on the keto diet. Your insulin levels drop when you restrict carbs, and low insulin makes it harder for your body to retain sodium and water.[9] Drink plenty of plain water, and sip on bone broth to replenish electrolytes, especially during the first couple of weeks when your body is adjusting to the new diet.
• High-protein ketogenic diet — This method is a variant of the SKD. In a high-protein diet, you increase the ratio of protein consumption to 10 percent and reduce your healthy fat consumption by 10 percent. In a study involving obese men that tried this method, researchers noted that it helped reduce their hunger and lowered their food intake significantly, resulting in weight loss.11
Paleo and keto can overlap, though there are some major differences in the core of each way of eating. The Paleo diet focuses on whole, natural foods that would have been available as food to our paleolithic ancestors. If it could have been hunted or foraged, then it would have been eaten. Some people on a Paleo plan also focus on what would have been growing in season, and in a certain region of the world for their genetic ancestors. Carbs are overall allowed in a Paleo plan, but they would come from whole foods like potatoes, sweet potatoes, fruits, honey, and other unprocessed sources.
Whatever the source of protein you consume, make sure they are organic grass fed and antibiotic-free, as they are generally healthier and safer for your body. In one study, researchers indicated that grass fed beef (regardless of cuts) contains more omega-3 acid and conjugated linoleic acid compared to grain-fed beef.21 As for non-meat sources of protein, try to look for organic and pesticide-free varieties.
There are so many tricks, shortcuts, and gimmicks out there on achieving optimal ketosis – I’d suggest you don’t bother with any of that. Optimal ketosis can be accomplished through dietary nutrition alone (aka just eating food). You shouldn’t need a magic pill to do it. Just stay strict, remain vigilant, and be focused on recording what you eat (to make sure your carb and protein intake are correct).

I’ve always heard that the brain functions well on ketones. Gluconeogenisis typically reduces ketosis, though as well? This is the first time I’ve heard anyone say the brain can’t use anything but glucose. I know there’s *preferred* sources of fuel over others, but I was also fairly certain other sources were fine.. or humans might be in a bit of trouble.

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