[iv] Hussein M Dashti, MD PhD FICS FACS, Thazhumpal C Mathew, MSc PhD FRCPath, Talib Hussein, MB ChB, Sami K Asfar, MB ChB MD FRCSEd FACS, Abdulla Behbahani, MB ChB FRCS FACSI PhD FICS FACS, Mousa A Khoursheed, MB ChB FRCS FICS, Hilal M Al-Sayer, MD PhD FICS FACS, Yousef Y Bo-Abbas, MD FRCPC, and Naji S Al-Zaid, BSc PhD. "Long-term effects of a ketogenic diet in obese patients"
When you eat foods high in carbohydrates and fat, your body naturally produces glucose. Carbohydrates are the easiest thing for the body to process, and therefore it will use them first – resulting in the excess fats to be stored immediately. In turn, this causes weight gain and health problems that are associated with high fat, high carbohydrate diets (NOT keto).
The classic ketogenic diet is a very low-carb diet plan that was originally designed in the 1920s for patients with epilepsy by researchers working at Johns Hopkins Medical Center. (1) Researchers found that fasting — avoiding consumption of all foods for a brief period of time (such as with intermittent fasting), including those that provide carbohydrates — helped reduce the amount of seizures patients suffered, in addition to having other positive effects on body fat, blood sugar, cholesterol and hunger levels. (2)
I’ve always heard that the brain functions well on ketones. Gluconeogenisis typically reduces ketosis, though as well? This is the first time I’ve heard anyone say the brain can’t use anything but glucose. I know there’s *preferred* sources of fuel over others, but I was also fairly certain other sources were fine.. or humans might be in a bit of trouble.
Each of the above methods is good for its own reason; however, we would suggest only one: the blood test.  The urine strips are cheap, yet not accurate.  The breath analyzer is expensive, difficult to find and has definite quirks.  The blood tests, while somewhat expensive, are fully reliable and testing your blood - the most accurate place to measure your ketones.
It truly depends from person to person. While some may be able to stay in ketosis while consuming 80 grams of carbs, others may not be so lucky. Quite a lot of people within the population can go quite high in their carbohydrate consumption and stay in ketosis, granted they have no blood sugar dysregulation. The longer you have followed the keto diet, the more your metabolism remains in ketosis after a higher carb consumption.

“This diet has changed my life. I always find it too easy to cheat because healthy foods are just awful, or so I thought. Once I read the Keto Fit Diet recipes my mouth was watering and I couldn’t wait to get started making these meals. They are delicious, my friends and family would never know I’m on a diet if it weren’t for the 35 lbs I’ve lost in the last 3 months.”
In a state of ketosis, your body breaks fat down in the liver and converts it into ketones to be used for energy. Fat doesn't generate an insulin response, so insulin levels remain stable. This makes it much harder to store excess fat, and easier to tap into body fat stores for energy. Not only will this allow you to maintain your weight, but it will greatly encourage weight loss.
Sleep enough – for most people at least seven hours per night on average – and keep stress under control. Sleep deprivation and stress hormones raise blood sugar levels, slowing ketosis and weight loss a bit. Plus they make much it harder to stick to a keto diet, and resist temptations. So while handling sleep and stress will not get you into ketosis on it’s own, it’s still worth thinking about.
In order to transition and remain in ketosis, aiming for about 30–50 net grams is typically the recommended amount of total carbs to start with. This is considered a more moderate or flexible approach but can be less overwhelming to begin with. Once you’re more accustomed to “eating keto,” you can choose to lower carbs even more if you’d like (perhaps only from time to time), down to about 20 grams of net carbs daily. This is considered the standard, “strict” amount that many keto dieters aim to adhere to for best results, but remember that everyone is a bit different.

• Standard ketogenic diet (SKD) — SKD is the type I typically recommend for most people, because it is very effective. It focuses on high consumption of healthy fats: As I explain in my book, "Fat for Fuel," you should aim for having 70 to 85 percent of your total daily calories to come from healthy fats. For your protein intake, the general rule of thumb is to follow the formula of 1 gram of protein for every kilogram of your lean body mass.
Many people also experience cramping, notably in the feet and legs. Because of this, you’ll want to consume extra electrolytes any time you are on a ketogenic plan. People who suffer with these symptoms refer to them as the Keto-Flu, and while it isn’t like the real flu, the symptoms can knock you down until you get your electrolytes back in balance.
“Your liver produces ketones all the time, but the rate depends on carbohydrate and protein intake,” says Jeff Volek, Ph.D., R.D., a professor of human sciences at Ohio State University. When the majority of your diet is made up of of carbs and protein, ketogenesis slows. Replacing carbs and protein with fat will put your body into ketosis, thus ramping up ketone production. This takes about three days to induce.

Something that makes the keto diet different from other low-carb diets is that it does not “protein-load.” Protein is not as big a part of the diet as fat is. Reason being: In small amounts, the body can change protein to glucose, which means if you eat too much of it, especially while in the beginning stages of the keto diet, it will slow down your body’s transition into ketosis.


Your glycogen stores can still be refilled while on a ketogenic diet. A keto diet is an excellent way to build muscle, but protein intake is crucial here. It’s suggested that if you are looking to gain mass, you should be taking in about 1.0 – 1.2g protein per lean pound of body mass. Putting muscle on may be slower on a ketogenic diet, but that’s because your total body fat is not increasing as much.5Note that in the beginning of a ketogenic diet, both endurance athletes and obese individuals see a physical performance for the first week of transition.
Every recipe is less than 10 grams of carbs per serving. All recipes are gluten free and made only from whole, real, easy to find foods that you can find at your local grocery store. New resources are added to the plans each week. All the best information to help keep you on track with your low carb, keto lifestyle. I've even included a journal where you can track what you eat, how much you moved and how you are feeling overall. It is definitely the most comprehensive low carb meal plan out there. And for only $4.99 per week, you simply cannot beat the price.
For endurance athletes, the transition to a ketogenic diet may reduce recovery time after training, but for casual exercisers, the transition to the ketogenic diet may make sticking with your fitness routine a challenge at first. (10) If you feel your energy levels drop too much when starting the ketogenic diet, slow down your reduction of carbohydrates, making sure to do it over time rather than all at once.
The ketogenic diet is based on the principle that by depleting the body of carbohydrates, which are its primary source of energy, you can force the body to burn fat for fuel, thereby maximizing weight loss. When you consume foods that contain carbohydrates, the body converts those carbohydrates into glucose, or blood sugar, which it then uses for energy. (1)
The information in the first section was great, but the recipes were not as helpful as I had hoped. The ingredients are very expensive - I spent $130 shopping for just the first three days of meals and that didn't include the leg of lamb, which I skipped. Also, as a working mom, I would consider the amount of kitchen time as extreme. As an example, Day One includes a one-hour baking project for breakfast, followed by deviled eggs with bacon and avocado as a mid-morning snack, followed by a cooked chicken lunch, then a smoothie mid-afternoon snack, and a leg of lamb dinner with a side. Again, that's just the first day. Section 1 was great and I learned a great deal about keto lifestyle and issues. I would love the author to revise the meal plan and recipe sections to limit each day to no more than 90 minutes in the kitchen including prepping foods like boiling eggs, frying bacon, or cooking chicken which aren't currently included in her recipes times.
Bonnie J. Brehm, Randy J. Seeley, Stephen R. Daniels, and David A. D’Alessio, “A Randomized Trial Comparing a Very Low Carbohydrate Diet and a Calorie-Restricted Low Fat Diet on Body Weight and Cardiovascular Risk Factors in Healthy Women,” The Journal of Clinical Endocrinology & Metabolism: Vol 88, No 4; January 14, 2009. http://press.endocrine.org/doi/full/10.1210/jc.2002-021480.
There are reasons a strange diet like this has stuck around since the 1920's.  A diet like keto that is low in sugar lowers blood glucose and insulin levels has several positive effects on the body, especially in overweight or obese people. The ketogenic diet gives your body the chance to re-adjust its glucose and insulin levels.  In addition, there are health benefits that will enhance daily life, as well as help treat disease.  Check out these benefits of the ketogenic diet:
Most alcoholic beverages don’t list the ingredients or nutritional information on the label, so be prepared and check your favorite drinks online so you know your limits beforehand. Most apps and trackers list many types of alcohol in their database, and this is the easiest way to be sure of what you’re drinking. Be warned, when you’re in ketosis your alcohol tolerance will go down, so you might not want to drink as much as you might be used to.
There are numerous benefits that come with being on keto: from weight loss and increased energy levels to therapeutic medical applications. Most anyone can safely benefit from eating a low-carb, high-fat diet. Below, you’ll find a short list of the benefits you can receive from a ketogenic diet. For a more comprehensive list, you can also read our in-depth article here >
Unfortunately, there’s no long-term data on ketogenic diets versus other diets. In a 2015 Italian study, those on a ketosis diet lost 26 pounds in three months. About half of the participants stayed on the diet for a year but lost little additional weight in the next nine months. People in a 2014 Spanish study who followed a very-low-calorie ketogenic diet lost an average of 44 pounds in a year—but a third of them dropped out, possibly because it was too hard to maintain.
Clinical improvement was observed in Alzheimer’s patients fed a ketogenic diet, and this was marked by improved mitochondrial function. (14a) In fact, a European Journal of Clinical Nutrition study pointed to emerging data that suggested the therapeutic use of ketogenic diets for multiple neurological disorders beyond epilepsy and Alzheimer’s, including headaches, neurotrauma, Parkinson’s disease, sleep disorders, brain cancer, autism and multiple sclerosis. (14b)
The keto diet changes the way your body converts food into energy. Eating a lot of fat and very few carbs puts you in ketosis, a metabolic state where your body burns fat instead of carbs for fuel. When your body is unable to get glucose from carbs, your liver converts fatty acids from your diet into ketones, an alternative source of energy. Burning ketones in place of glucose reduces inflammation and spurs weight loss.[1] 
I believe (as well as the numerous experts I have interviewed) that over 90 percent of cancer cases are either preventable or treatable. The key here is to view cancer as a metabolic dysfunction, allowing you to gain control over this dreadful disease. Simply put, the right foods and strategies may help suppress cancer growth while simultaneously pushing it into remission.
As of the moment, there is no industry standard as to how many calories should be consumed in a restricted ketogenic diet, but there are published studies that provide estimates. In one example, a 65-year-old woman who was suffering from glioblastoma multiforme (GBM), an aggressive type of brain cancer, was put into a restricted ketogenic diet that started with water fasting and then proceeded to consuming 600 calories a day only.
The best place to get started if you’re interested in the ketogenic diet is to first take a look at the fats you can incorporate, such as avocado, olive oil, or cacao butter. You could also take a look at more of an animal-based fat like grass-fed tallow or pasteurized lard or, if you are not too sensitive to butter, grass-fed butter is a really good option.
Each of the above methods is good for its own reason; however, we would suggest only one: the blood test.  The urine strips are cheap, yet not accurate.  The breath analyzer is expensive, difficult to find and has definite quirks.  The blood tests, while somewhat expensive, are fully reliable and testing your blood - the most accurate place to measure your ketones.
Exogenous ketones, or ketones that are produced in a lab and then consumed, have been compared to jet fuel, both as a fuel for the brain and body, and as a flavor comparison. It’s like kick-starting ketosis, or enhancing it, since you wind up with vastly more ketone bodies in circulation with a concurrent drop in blood glucose. The best, most effective, and safest version of exogenous ketones currently available are ketone salts. They can potentially get you into ketosis faster, and help you reap the benefits of a low carb diet, but they’re still relatively new to the market (12).

Some people like to start a ketogenic diet, or restart one, with a more restrictive plan. These aren’t for everyone, since most people adjust better to slow, gradual changes. If you’re the kind of person who likes to change everything all at once, you can try one of these short term hacks to get you kick-started in keto, and maybe even help you lose those first couple of pounds, or the last couple that just won’t seem to budge.


“Your liver produces ketones all the time, but the rate depends on carbohydrate and protein intake,” says Jeff Volek, Ph.D., R.D., a professor of human sciences at Ohio State University. When the majority of your diet is made up of of carbs and protein, ketogenesis slows. Replacing carbs and protein with fat will put your body into ketosis, thus ramping up ketone production. This takes about three days to induce.
This also enables you to see what you were eating prior to a woosh of weight loss, or a stall, or even a gain. You can see possible triggers for these events, like having extra vegetables, or having too many nuts and cheeses. It also lets you see if you may have sensitivities. If you try a week without dairy but keep your calories the same, for example, you may or may not notice a spontaneous drop in weight.
Eating healthier, losing weight, and trimming your waistline―no matter what your reasons for following the ketogenic diet are, starting is never as simple as it sounds. Equipping you with easy-to-follow meal plans, shopping lists, and need-to-know info about the keto lifestyle, The Complete Ketogenic Diet for Beginners is your all-in-one resource for starting and sticking to the ketogenic diet. Key into keto and learn how good it can feel to lose weight and lead a healthy lifestyle with The Complete Ketogenic Diet for Beginners cookbook.
Those issues can be part of what's known as the “keto flu,” Warren says. Other side effects of the keto diet, all of which are tied to carb withdrawal, can include lightheadedness, nausea, mental fog, cramps, and headaches, in addition to tiredness. Luckily, the keto flu doesn't usually last more than a week—which is coincidentally about when people start to see the number on the scale go down, says Warren.

Fats are great if you want to add flavor and texture to your meals, and will help you feel full. Some people believe swear by coconut oil, and whether or not the claimed health benefits are actually present, it’s one of the fats that you might want to add to your diet. Butter is an excellent choice, as is ghee (Indian clarified butter). Duck fat is highly prized. Avocado oil is a great choice when making dressings or sauces, as it’s liquid at room temperature and has a mild flavor. The fats and oils listed here are primarily saturated, and they are the least likely to go rancid and produce free radicals and inflammation in the body (5, 6).
• Athletic Performance Impediments: For those people who train heavy and hard, going keto might cramp your style. As important as protein is for muscle growth, carbs also play an equally critical role by releasing insulin to drive that protein into muscles faster. It also helps us build up glycogen stores for longer training sessions, runs or hikes. One comprehensive review of the literature in sports nutrition found that while research is lacking on the long-term impacts of the keto diet, in the short term, the keto diet is inferior to other diet protocols on anaerobic, aerobic and in some cases even strength performance measures.
Some people also experience a change in bathroom habits. Moving your bowels can be difficult with a dramatic change in diet, and can be helped by choosing specific foods over others. Cheese is well known to stop up the works, so reducing cheese can help. Making sure to include plenty of fibrous vegetables can also keep things moving, so make sure to get lots of leafy greens, celery, and other veggies. In addition, make sure to drink enough water. Water not only keeps you hydrated, but also helps keep the bowels moving.

In my book "Fat for Fuel," I sought to educate readers about the benefits of using healthy fats as a catalyst to bring about improved mitochondrial function, thus allowing you to achieve better health. In essence, the book answers WHY it is important for you to consume healthy fats. However, you still need to know HOW to prepare the right ketogenic foods in an appetizing way.

One of the secrets of getting into ketosis faster is by fasting, since this helps burn off stored glycogen, so trying intermittent fasting can help you on your way. While it isn’t necessary to be on a ketogenic diet, doing IF while on a ketogenic diet can be very helpful. Most people who do IF don’t even think about food until late in the morning because it becomes natural to wait until later to eat.


On a keto diet, weight loss can often be substantial and happen quickly (especially for those who start the diet very overweight or obese). The 2013 study published in the British Journal of Nutrition found that those following a keto diet “achieved better long-term body weight and cardiovascular risk factor management when compared with individuals assigned to a conventional low-fat diet (i.e. a restricted-energy diet with less than 30 percent of energy from fat).” (4)
This process of burning fat provides more benefits than simply helping us to shed extra weight — it also helps control the release of hormones like insulin, which plays a role in development of diabetes and other health problems. When we eat carbohydrates, insulin is released as a reaction to elevated blood glucose (an increase in sugar circulating in our blood) and insulin levels rise. Insulin is a “storage hormone” that signals cells to store as much available energy as possible, initially as glycogen (aka stored carbohydrates in our muscles) and then as body fat.
Almost all commercially produced mayo has sugar added (WHY!?) among other crap ingredients. Good mayo is just oil, egg, acid (vinegar or lemon juice) and salt, so perfectly in line with the dietary guidelines for keto or paleo etc. It only takes 30 seconds to make you own and I haven’t gone back since I learned that, but check out Primal Kitchen if you want to buy a better quality version. Mayo represent.

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