There are several medical studies — such as two conducted by the Department of Radiation Oncology at the Holden Comprehensive Cancer Center for the University of Iowa, and the National Institutes of Health’s National Institute of Neurological Disorders and Stroke, for example — that show the ketogenic diet is an effective treatment for cancer and other serious health problems. (12)
A lot of changes are happening in your body and you’re going to feel it! The first five to seven days can be pretty rough, but your body is getting over its dependency on sugar. During this time of transition it is essential that you supplement electrolytes. Your body is flushing out lots of water, and with that goes electrolytes. The Keto Flu can be greatly reduced if you add sodium, potassium and magnesium to your diet. Check out our supplements page for a list of electrolyte supplements we recommend. Stay on course and you’ll start feeling better in no time!
I’m honestly a little skeptical about it the idea of keto permanently. My brief glance at the literature seems to imply that it can have side effects of kidney stones, skeletal fractures, and slow the growth rate of children, but that was a study on kids with epilepsy (which it treated very effectively), so who knows how that applies to adults. And the other studies I found dealt with overweight and obese subjects, so it may be hard to find something on the long term effects on otherwise healthy adults.

Don’t stick to chicken and steak just because you’re comfortable cooking them. Make dinner time the place where you can try new meats and recipes that increase your keto recipe resources. “At lunch and dinner, you can be creative and experiment,” Weaver says. “Just focus on cooking meat—pork, chicken, lamb, beef, or seafood. Meat is rich in iron and fish contains omega-3 fatty acids and vitamin D. Use only organic oils, such as avocado oil, coconut oil, and olive oil.”
Diets high in healthy fats and protein also tend to be very filling, which can help reduce overeating of empty calories, sweets and junk foods. (6) For most people eating a healthy low-carb diet, it’s easy to consume an appropriate amount of calories, but not too many, since things like sugary drinks, cookies, bread, cereals, ice cream or other desserts and snack bars are off-limits.

This short-term hack originated in clinical settings to help obese patients shed excess fat quickly.  It was described in Dr. Atkins’ New Diet Revolution for the same purpose. The diet consists of 1000 calories or less of almost entirely fat, with a little protein. This can be useful for people who have been on a ketogenic diet for at least three weeks, or who have had a weight plateau that has lasted at least three weeks. Since it’s so high in fat, you have to be keto-adapted for it to be effective, not just in ketosis.
Each of the above methods is good for its own reason; however, we would suggest only one: the blood test.  The urine strips are cheap, yet not accurate.  The breath analyzer is expensive, difficult to find and has definite quirks.  The blood tests, while somewhat expensive, are fully reliable and testing your blood - the most accurate place to measure your ketones.
If you're new to keto, watch out for hidden carbs. Generally, dairy products and nuts are a good way to meet your daily fat intake, but know that some of those items may contain more carbohydrates than you think. For example, yogurt topped with nuts may seem like a great keto-friendly snack, but a 5.3 ounce serving of plain yogurt has 12 grams of carbohydrates. Vanilla flavored yogurt has 24 grams of carbohydrates. Add an ounce of cashews, weighing in at nearly nine grams of carbs, and you’re up to 21 to 33 grams of carbs for that snack, which could knock you out of ketosis. Be sure to read nutrition labels carefully and pay careful attention to serving sizes. Track foods using a keto-specific app like Senza or KetoDiet can help you stay within your recommended daily carb intake.
But all those studies were very small, and not all research on the keto diet is as promising. One American Society for Clinical Nutrition study of 20 participants found that those on the diet didn’t lose more weight than those on a non-keto diet. But they did have fouler moods and higher levels of inflammation, which has been linked to a variety of conditions, including heart disease and cancer.
During week 1 (and sometimes week 2) your body is transitioning to this whole new metabolic state, and there may be some initial side effects.  These are collectively known as the "keto flu".  The good thing is that if you don't take them for granted and think you're "superman" and that your body will be different, you can easily prevent these symptoms.
Reduced hunger. Many people experience a marked reduction in hunger on a keto diet. This may be caused by an increased ability of the body to be fueled by its fat stores. Many people feel great when they eat just once or twice a day, automatically ending up doing a form of intermittent fasting. This saves both time and money, while also speeding up weight loss.

After about two to seven days of following this eating routine, you go into something called ketosis, or the state your body enters when it doesn't have enough carbs for your cells to use for energy. Then it starts making ketones, or organic compounds that your bod then uses in place of those missing carbs—and oh, it also burns fat for more energy, says Beth Warren, R.D., founder of Beth Warren Nutrition and author of Living A Real Life With Real Food.
• Standard ketogenic diet (SKD) — SKD is the type I typically recommend for most people, because it is very effective. It focuses on high consumption of healthy fats: As I explain in my book, "Fat for Fuel," you should aim for having 70 to 85 percent of your total daily calories to come from healthy fats. For your protein intake, the general rule of thumb is to follow the formula of 1 gram of protein for every kilogram of your lean body mass.
This process of burning fat provides more benefits than simply helping us to shed extra weight — it also helps control the release of hormones like insulin, which plays a role in development of diabetes and other health problems. When we eat carbohydrates, insulin is released as a reaction to elevated blood glucose (an increase in sugar circulating in our blood) and insulin levels rise. Insulin is a “storage hormone” that signals cells to store as much available energy as possible, initially as glycogen (aka stored carbohydrates in our muscles) and then as body fat.
There are variations of the ketogenic diet that are implemented for a variety of reasons.  One of the top reasons these variations are used are for athletes who are not getting the necessary energy required for their intense workouts.  There are also those who enjoy the benefits of ketosis, but they just do not feel the same without a carb refeed day every now and then.

There are several medical studies — such as two conducted by the Department of Radiation Oncology at the Holden Comprehensive Cancer Center for the University of Iowa, and the National Institutes of Health’s National Institute of Neurological Disorders and Stroke, for example — that show the ketogenic diet is an effective treatment for cancer and other serious health problems. (12)
It comes down to simple mathematics. In order to stay in ketosis, you need to eat a very very low number of carbs. And if you eat too much protein, this can actually knock you out of ketosis as well. Therefore, if you’re eating almost no carbs, and you are eating moderate amounts of protein, the ONLY remaining macronutrient you can consume to fill you up each day would be fat. Add in that consuming fat allows you to stay in ketosis, and you are consuming a high fat, medium protein, low carb diet.

Ketosis is the result of following the standard ketogenic diet, which is why it’s also sometimes called “the ketosis diet.” Ketosis takes place when glucose from carbohydrate foods (like grains, all sources of sugar or fruit, for example) is drastically reduced, which forces the body to find an alternative fuel source: fat. Ketosis can also be achieved by multiple days of total fasting, but that isn’t sustainable beyond a few days. (It’s why some keto diet plans combine intermittent fasting or IMF with the keto diet for greater weight loss effects.)
Although studies have shown that the keto diet can reduce seizures for children with epilepsy, there is no evidence indicating that keto helps with other brain disorders or improves mental cognition, according to Harvard Health Publishing. Some studies show that keto may lower blood sugar for people with type 2 diabetes, but there is not enough long-term research to determine whether it’s safe and effective for diabetics.
KetoVale‘s Tip:  Exogenous ketones are NOT a magic pill or a carb blocker. You should be making better choices about your diet meal plan first and then ask yourself if you want to or how you can supplement afterward to help out. Remember it’s a supplement and not supposed to be used as an eraser to erase eating choices (by definition, supplement is a thing added to something else in order to complete or enhance it). It’s like building muscles, you can take supplements, but if you don’t workout and eat right, the muscles won’t show up. The supplements aren’t going to lift those heavy weights for you. There’s no magic bullet.
But people who started following the keto diet noticed weight loss for a few reasons: When you eat carbs, your body retains fluid in order to store carbs for energy (you know, in case it needs it). But when you’re not having much in the carb department, you lose this water weight, says Warren. Also, it's easy to go overboard on carbohydrates—but if you're loading up on fat, it may help curb cravings since it keeps you satisfied.

KetoVale‘s Tip:  Exogenous ketones are NOT a magic pill or a carb blocker. You should be making better choices about your diet meal plan first and then ask yourself if you want to or how you can supplement afterward to help out. Remember it’s a supplement and not supposed to be used as an eraser to erase eating choices (by definition, supplement is a thing added to something else in order to complete or enhance it). It’s like building muscles, you can take supplements, but if you don’t workout and eat right, the muscles won’t show up. The supplements aren’t going to lift those heavy weights for you. There’s no magic bullet.
The hallmark of a ketogenic diet is being in ketosis for extended periods of time, and is achieved by carbohydrate restriction. While there isn’t a strict prohibition of artificial sweeteners, grains, and manufactured foods, there is a strong preference in the community to lean towards natural, whole foods. Keto is for overall health, and weight loss is a welcome side effect for many people.
On a ketogenic diet, your entire body switches its fuel supply to run mostly on fat, burning fat 24-7. Insulin levels become very low, and fat burning increases dramatically. It becomes easy to access your fat stores to burn them off. This is great if you’re trying to lose weight, but there are also other less obvious benefits, such as less hunger and a steady supply of energy. This may help keep you alert and focused.

•Sodium: Believe it or not, depending on your diet, you may be low on salt. When carb intake is low and insulin isn't being excreted, the kidneys absorb less sodium and potassium and excrete more as waste, leaving you feeling dizzy, fatigued and grumpy. Rather than reaching for more processed food, try seasoning your food a little more liberally with sea salt.


The book contains a two week menu for beginners. (Face it, there's a 90% chance you won't follow it to the letter, but it does help set your thinking in the right direction.) For each individual week there's a shopping list which, by itself, will help you adjust your kitchen quite a bit. There are tips on the best sweeteners (Swerve over Splenda), the oils you'll need, produce, canned and bottled items, pantry items, and meats. Something to consider as you go along is that some items, like almond and coconut flour are expensive items to stock up on, but you'll use considerably less than non-keto recipes will use for regular flour. Do what you can afford. Just know that there are some must-have staples like coconut oil and olive oil.
Yancy WS Jr, Westman EC, McDuffie JR, Grambow SC, Jeffreys AS, Bolton J, Chalecki A, Oddone EZ, “A randomized trial of a low-carbohydrate diet vs orlistat plus a lowfat diet for weight loss,” Arch Intern Med. 2010 Jan 25;170(2):136-45. http://www.ncbi.nlm.nih.gov/pubmed/20101008?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2.
One of the most common side effects of starting the ketogenic diet is the “keto flu.” This term describes the often unpleasant, fatigue-inducing symptoms that occur as the body adjusts from a high-carbohydrate to a low-carbohydrate diet. During the keto flu, the body’s stored glucose begins depleting, and the body starts adapting to producing and utilizing ketones as energy. (2)

Steve, thank you for the amazing article! Your style of writing was so funny and easy to follow, and had me actually laughing out loud so many times! Low carb is the only diet that has ever worked for me. I freaking love it. I got away from it, though, and started eating too much sugar again. My daughter is getting married next year, and I have to squeeze this badonkadonk into a cute dress next year, hopefully without looking like a mama hippo, so low carb it is. I see the basic program is the same, but there have been some advancements with the science of the diet which is great. I’m excited to get at it! Today is day 1 for me. Wish me luck; I’m going in…..

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